Acute cytomegalovirus infection and venous thrombosis: role of antiphospholipid antibodies

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1: J Infect. 2007 Jan;54(1):e47-50. Epub 2006 May 15.Related Articles, Links
Comment in:
J Infect. 2007 May;54(5):516-7.

Acute cytomegalovirus infection and venous thrombosis: role of antiphospholipid antibodies.

Delbos V, Abgueguen P, Chennebault JM, Fanello S, Pichard E.

Service des Maladies Infectieuses et tropicales, Centre Hospitalier Universitaire, 4 rue Larrey, 49933 Angers Cedex 9, France. VaDelbos@chu-angers.fr

Cytomegalovirus (CMV)-induced thrombosis has been reported in immunocompromised patients, such as transplant recipients and patients with AIDS. Recent cases also describe thrombotic phenomena in immunocompetent patients with CMV infection. Various mechanisms may explain the role of CMV in thrombosis: this virus can damage endothelial cells, activate coagulation factors, and induce production of antiphospholipid (aPL) antibodies. We present a case report of a previously healthy white woman with a pulmonary embolism associated with CMV infection and the presence of aPL antibodies, and we discuss the role of the aPL antibodies associated with CMV infection in the pathogenesis of thrombosis.

Publication Types:
Case Reports

PMID: 16701900 [PubMed - indexed for MEDLINE]

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Display SummaryBriefAbstractAbstractPlusCitationMEDLINEXMLUI ListLinkOutASN.1Related ArticlesCited in BooksCancerChrom LinksDomain Links3D Domain LinksdbGaP LinksGEO DataSet LinksGene LinksGene (OMIM) LinksGene (GeneRIF) LinksGenome LinksProject LinksGENSAT LinksGEO Profile LinksHomoloGene LinksNucleotide LinksNucleotide (RefSeq) LinksNucleotide (Weighted) LinksEST LinksEST (RefSeq) LinksGSS LinksGSS (RefSeq) LinksOMIA LinksOMIM (calculated) LinksOMIM (cited) LinksBioAssay LinksCompound LinksCompound (MeSH Keyword)Compound (Publisher) LinksSubstance LinksSubstance (MeSH Keyword)Substance (Publisher) LinksPMC LinksCited in PMCPopSet LinksProbe LinksProtein LinksProtein (RefSeq) LinksProtein (Weighted) LinksProtein Cluster LinksCited ArticlesSNP LinksSNP (Cited)SRA LinksStructure LinksTaxonomy via GenBankUniGene LinksUniSTS Links Show 5102050100200500Sort ByPub DateFirst AuthorLast AuthorJournalTitleSend toTextFilePrinterClipboardCollectionsE-mailOrderAbout Entrez
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