Elevated Rising CA 125 with Adenomyosis -------------------------------------------------------------------------------- To cite this paper: Mitchel

Elevated Rising CA 125 with Adenomyosis

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To cite this paper:
Mitchel S. Hoffman, William N. Spellacy. Journal of Gynecologic Surgery. March 1, 2001, 17(1): 33-34. doi:10.1089/104240601750200387.

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Mitchel S. Hoffman, MD
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of South Florida College of Medicine Tampa, Florida
William N. Spellacy, MD
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of South Florida College of Medicine Tampa, Florida
Elevated serum CA 125 is useful in the management of ovarian cancer but has also been associated with several benign conditions. This is a report of a patient with an elevated, rising serum CA 125 level who was found to have a benign process. A 48-year-old woman with a 16-week-size uterus was thought to have leiomyomata uteri. Her serum CA 125 level was initially 150 u/ml; on repeat determination 10 weeks later, it was 391 u/ml. Laparotomy with bilateral salpingo-oophorectomy and hysterectomy revealed pathologic changes only in the uterus, the uterine weight being 718 g. Histologically, the lesion proved to be extensive adenomyosis. Severe uterine adenomyosis may be associated with both an elevated and a rising serum CA 125 level.


This paper was cited by:
Serum CA-125 Levels in Women with Uterine Leiomyomata And A Review of The Literature
Marisa Fraraccio Baker, Joan McCarthy, William N. Spellacy, Rosemary P. Cardosi
Journal of Gynecologic Surgery. Mar 2007, Vol. 23, No. 1: 19-22