Retinopathy following measles, mumps, and rubella vaccination in an immuno-incompetent girl

Retinopathy following measles, mumps, and rubella vaccination in an immuno-incompetent girl.

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Schuil J, van de Putte EM, Zwaan CM, Koole FD, Meire FM

Int Ophthalmol 1998; 22:345-7.

Abstract
We describe a 4-year-old girl with subnormal visual acuity due to a bilateral retinopathy. The child had a history of encephalitis following MMR vaccination. Temporary retinopathy associated with measles, mumps, and rubella (MMR) vaccination has been described. Recently an idiopathic CD4+ T lymphocytopenia in the child was diagnosed. This cellular immunodeficiency supports our hypothesis of measles retinopathy after vaccination of an immuno-deficient child.

MeSH
CD4-Positive T-Lymphocytes; Child, Preschool; Diagnosis, Differential; Female; Humans; Immunoglobulin G; Measles; Measles Vaccine; Measles-Mumps-Rubella Vaccine; Mumps; Mumps Vaccine; Retinal Diseases; Rubella; Rubella Vaccine; T-Lymphocytopenia, Idiopathic CD4-Positive; Vaccines, Combined; Visual Acuity

CAS Registry Number (Substance Name)
0 (Immunoglobulin G), 0 (Measles Vaccine), 0 (Measles-Mumps-Rubella Vaccine), 0 (Mumps Vaccine), 0 (Rubella Vaccine), 0 (Vaccines, Combined)

Author Address
Bartiméus Institute of Visually Impaired Children, Zeist, The Netherlands.

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